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Central administration of palmitoylethanolamide decreases hyperalgesia in mice through inhibition of NF‐κB nuclear signalling in dorsal root ganglia. Eur J Pharmacol‐acylethanolamines (NAEs), endogenous biologically Energetic lipids such as the endogenous cannabinoid receptor ligand anandamide plus the satiety component oleoylethanolamide. PEA